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Patents

2022​

-NaÈ›ional patent application submitted:    

Title: „Reporter cell line for testing the activity of IL-1β synthesis and secretion modulators"- Marioara Chiritoiu-Butnaru1, Gabriela Chiritoiu1, Simona Ghenea1, Gheorghita Isvoranu2, 

1.   Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

2.  "Victor BabeÈ™" National Institute of Pathology, Bucharest, Romania

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Publications

2021

1. "Therapeutic potential of interleukin-15 in cancer (Review)" Gheorghita Isvoranu, Mihaela Surcel, Adriana Narcisa Munteanu, Ovidiu Gabriel Bratu, Florentina Ionita-Radu, Monica Teodora Neagu, Marioara Chiritoiu-Butnaru,  Experimental and Therapeutic Medicine, 2021 Jul;22(1):675 doi: 10.3892/etm.2021.10107. Epub 2021 Apr 24

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2. "Dataset of human EDEM2 melanoma cells proteomics, affinity proteomics and deglycoproteomics" Gabriela N. ChiriÈ›oiu, Marioara ChiriÈ›oiu, Cristian V.A. Munteanu, Data in Brief Volume, 2021, doi: 10.1016/j.dib.2021.107471

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Conferences

2020

1. Oral presentation:  "Non-conventional proteins involved in interleukin-1β secretion from primary macrophages"

Nathalie Brouwers (1), Gheorghița Isvoranu (2), Ștefana M. Petrescu (3), Vivek Malhotra (1), Marioara Chiriţoiu (1,3)

  • 1. Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology,

Barcelona, Spain

  • 2. "Victor BabeÈ™" National Institute of Pathology, Bucharest, Romania

  • 3. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

A 4-a Conferință a AsociaÈ›iei Române de Imuno-Dermatologie, A 49-a Conferință a Societății de Imunologie din România

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2. Oral presentation: "Caracteristici fenotipice ale celulelor NK induse de prezenÈ›a celulelor tumorale"  GheorghiÈ›a Isvoranu (1), Mihaela Surcel (1), Adriana Narcisa Munteanu (1), Ioana-Ruxandra Pîrvu (1), Monica Teodora Neagu (1)

  • 1. "Victor BabeÈ™" National Institute of Pathology, Bucharest, Romania; 

  • 2.  University of Bucharest, Faculty of Biology, Bucharest, Romania

A 4-a Conferință a AsociaÈ›iei Române de Imuno-Dermatologie, A 49-a Conferință a Societății de Imunologie din România

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2021:

1. Oral presentation: "Proteine neconvenÈ›ionale implicate în secreÅ£ia interleukinei-1β din macrofage primare"

Nathalie Brouwers (1), Gheorghița Isvoranu (2), Ștefana M. Petrescu (3), Vivek Malhotra (1), Marioara Chiriţoiu (1,3)

  • 1. Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology,

Barcelona, Spain

  • 2. "Victor BabeÈ™" National Institute of Pathology, Bucharest, Romania

  • 3. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

ConferinÈ›a Cercetării ȘtiinÈ›ifice din Academia Română (CCSAR-2021)

 

2. Poster: "Phenotypic and functional characterisation of NK cells in metastatic melanoma"

Gheorghita Isvoranu (1), Mihaela Surcel (1), Adriana Narcisa Munteanu (1,2), Carolina Constantin (1,3),  Emilia Manole (1,3), Marioara Chiritoiu-Butnaru (4), Monica Teodora Neagu (1,2,3)

  • 1 „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

  • 2. Doctoral School of Biology, Faculty of Biology, University of Bucharest, Bucharest, Romania

  • 3 Colentina Clinical Hospital; Bucharest, Romania

  • 4 Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

2nd International Conference „Cancer Metastasis“

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3. Poster: "Natural Killer Cells Immunophenotyping in Metastatic Melanoma"

Gheorghita Isvoranu (1), Mihaela Surcel (1), Adriana Narcisa Munteanu (1,2), Ioana Ruxandra Pirvu (1), Carolina Constantin (1,3),  Emilia Manole (1,3), Marioara Chiritoiu-Butnaru (4), Monica Teodora Neagu (1,2,3)

  • 1 „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

  • 2. Doctoral School of Biology, Faculty of Biology, University of Bucharest, Bucharest, Romania

  • 3 Colentina Clinical Hospital; Bucharest, Romania

  • 4 Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

International Pathology Conference of „Victor BabeÈ™” Institute, Romania, 04-06.11.2021, eveniment online.

 

4. Poster: "Phenotypic and functional characterization of NK cells in metastatic melanoma" Gheorghita Isvoranu, Mihaela Surcel, Adriana-Narcisa Munteanu, Carolina Constantin, Emilia Manole, Marioara Chiritoiu-Butnaru, Monica-Teodora Neagu.

  • 1 „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

  • 2. Doctoral School of Biology, Faculty of Biology, University of Bucharest, Bucharest, Romania

  • 3 Colentina Clinical Hospital; Bucharest, Romania

  • 4 Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

2nd International Conference „Cancer Metastasis”, Austria, 13-17.12.2021, eveniment online.

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2022

1. Poster: "Phenotypic changes in tumor-primed murine NK cells” Gheorghita Isvoranu1, Carolina Constantin1, Mihaela Surcel1, Adina-Narcisa Munteanu1, Marioara Chiritoiu-Butnaru2, Monica Neagu1, 

  • 1 „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

  • 2. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

8th Symposium on Advances in Cancer Immunology and Immunotherapy, 1-3 Decembrie 2022, Athens, Greece

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2. Oral presentation: "CRISPR-mediated generation of a reporter cell line to study (neuro)inflammation” Gabriela Chiritoiu1, Simona Ghenea1, Gheorghita Isvoranu2, Marioara Chiritoiu-Butnaru1

  • 1. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania 

  • 2. „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

Congresul Universității de Medicină È™i Farmacie “Carol Davila” din BucureÈ™ti, 10-12 Noiembrie 2022, Bucuresti, Romania

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3. Oral presentation: "Generation of a Receptor Cell Line Suitable for High Throughput Screening of Molecules with Anti-Inflammatory Capacity"  - Gabriela Chiritoiu1, Simona Ghenea1, Cristian V.A. Munteanu1, Cosmin Trif1, Costin Ioan Popescu1, Laurentiu Spiridon1, Mihaela Uta1, Livia Sima1, Sorin Tunaru1, Stefana M. Petrescu1, Gina Simion2, Gheorghita Isvoranu2, Marioara ChiriÅ£oiu-Butnaru1

  • 1. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania 

  • 2. „Victor BabeÈ™” National Institute of Pathology, Bucharest, Romania

EU-OPENSCREEN DRIVE Workshop 2021- “Medicinal chemistry in drug discovery, new therapeutical approaches”H2020 - INFRADEV-03-2018-2019 Ensuring long-term sustainability of excellence in chemical biology within Europe and beyond- 19 Octombrie 2022, Timisoara, Romania

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4. Poster: “Generation of a reporter cell line to study (neuro)inflammation” Gabriela Chiritoiu1, Simona Ghenea1, Gheorghita Isvoranu2, Marioara Chiritoiu-Butnaru1

1. Institute of Biochemistry of the Romanian Academy, Bucharest, Romania

2. "Victor BabeÈ™" National Institute of Pathology, Bucharest, Romania

Cell Symposia: The Biology of Neuropsychiatric Disorders, 15-17 Mai 2022, Sitges, Spain

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